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. 2019 Jun 6;34(4):153–160. doi: 10.1097/YIC.0000000000000271

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Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Fig. 2 — Efficacy assessments across study period (FAS, MMRM). IV vortioxetine + oral vortioxetine, n = 27; IV placebo + oral vortioxetine, n = 28. Treatment differences are based on the least squares means; error bars represent standard errors. CGI-I, Clinical Global Impressions-Improvement; CGI-S, Clinical Global Impressions-Severity of Illness; FAS, full-analysis set; HADS-A, Hospital Anxiety and Depression Scale-Anxiety; HADS-D, Hospital Anxiety and Depression Scale-Depression; IV, intravenous; MADRS, Montgomery Åsberg Depression Scale; MMRM, mixed model for repeated measurements.