Table 4.
Comparison of 100% insulin degludec (IDeg) and 75%IDeg for glycaemic ranges, hypoglycaemic events, coefficient of variation (CV) and for glycaemia based on the first (first 48 h) and last exercise phase (last 48 h)
| 100% IDeg | 75% IDeg | P | |
|---|---|---|---|
| First phase (first 48 h) | |||
| Timeeuglycaemia, min | 1560 (1343‐2880) | 1738 ± 680 | 0.15 |
| Timeeuglycaemia, % | 59 (48‐76) | 63 ± 11 | 0.28 |
| Timehypoglycaemia, min | 90 (23‐390) | 60 (23‐428) | 0.99 |
| Timehypoglycaemia, % | 4 (1‐8) | 2 (1.5‐15) | 0.87 |
| Timehyperglycaemia, min | 953 ± 533 | 1003 ± 248 | 0.74 |
| Timehyperglycaemia, % | 35 ± 20 | 34 ± 18 | 0.66 |
| Hypoglycaemic events, n (per participant per 5 days) | 2.1 ± 1.3 | 2 (1‐3.5) | 0.67 |
| CVglycaemia, % | 37 ± 8 | 36 ± 6 | 0.69 |
| Last phase (last 48 h) | |||
| Timeeuglycaemia, min | 1497 ± 338 | 1653 ± 479 | 0.20 |
| Timeeuglycaemia, % | 55 ± 13 | 62 ± 16 | 0.16 |
| Timehypoglycaemia, min | 105 (30‐248) | 75 (15‐188) | 0.71 |
| Timehypoglycaemia, % | 4 (1‐10) | 3 (0.5‐7) | 0.71 |
| Timehyperglycaemia, min | 1055 ± 502 | 783 ± 39 | 0.13 |
| Timehyperglycaemia, % | 38 ± 18 | 30 ± 15 | 0.17 |
| Hypoglycaemic events (n) | 2.3 ± 1.6 | 1.9 ± 1.5 | 0.46 |
| CVglycaemia, % | 38 ± 8 | 41 ± 11 | 0.53 |
Abbreviations: CV, coefficient of variation; IDeg, insulin degludec.
Values are given as mean ± SD or median (25‐75 percentile).