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. 2018 Dec 4;19(4):1061–1071. doi: 10.1111/ajt.15173

Table 1.

Comparison of donor and preservation characteristics of livers in the preclinical study (Part A)

DHOPE (n = 6) Control (n = 9) P value
Donor characteristics
Age (y) 64 (57‐70) 62 (52‐64) .29
Sex (male) 3 (50%) 6 (67%) .62
Type of donor .23
DCD 6 (100%) 6 (67%)
DBD 0 3 (33%)
Cause of death .57
Cardiovascular 2 (33%) 1 (11%)
Post anoxic brain injury 2 (33%) 4 (44%)
Trauma 2 (33%) 4 (44%)
Reason rejected for transplantation .35
Age (DCD >60 y) 5 (83%) 4 (44%)
Expected steatosis 1 (17%) 3 (33%)
High transaminases 0 1 (11%)
Unknown 0 1 (11%)
Preservation characteristics
Cold ischemia time (min)a 489 (452‐513) 509 (409‐660) .72
Time from withdrawal of life support to cold flushb (min) 33 (26‐53) 43 (38‐79) .13
Time from circulatory arrest to cold flushc (min) 15 (13‐23) 20 (16‐23) .49

Data are presented as number (percentage) or median (interquartile range).

DCD, donation after circulatory death; DBD, donation after brain death.

a

Cold ischemia time was defined as the interval between start aortic cold flush in the donor until the start of NMP or DHOPE.

b

The time interval between the discontinuation of mechanical ventilation and the start of aortic cold flush in the donor (international donor warm ischemia time).

c

The time interval between cardiac arrest and the start of aortic cold flush in the donor.