Table 3.
Comparison of donor and recipient characteristics of transplanted livers (Part B)
| DHOPE (n = 10) | Control (n = 9) | P value | |
|---|---|---|---|
| Donor characteristics | |||
| Age (y) | 53 (47‐57) | 55 (50‐57) | .90 |
| Sex (male) | 5 (50%) | 5 (57%) | .46 |
| Type of donor | 1.00 | ||
| DCD | 10 (100%) | 9 (100%) | |
| DBD | 0 | 0 | |
| Cause of death | .73 | ||
| Cerebrovascular accident | 3 (30%) | 5 (56%) | |
| Post anoxic brain injury | 3 (30%) | 2 (22%) | |
| Trauma | 4 (40%) | 2 (22%) | |
| Recipient characteristics | |||
| Age (y) | 57 (54‐62) | 57 (53‐62) | .12 |
| Sex (male) | 6 (60%) | 4 (44%) | 1.00 |
| MELD score | 16 (15‐22) | 22 (17‐25) | .12 |
| Preservation characteristics | |||
| Cold ischemia time (min)a | 311 (282‐357) | 430 (424‐487) | <.001 |
| Time from withdrawal of life support to cold flush (min)b | 27 (23‐43) | 36 (29‐55) | .46 |
| Time from circulatory arrest to cold flush (min)c | 15 (13‐17) | 17 (15‐19) | .41 |
| Surgical variables | |||
| Estimated blood loss (mL) | 3600 (1763‐4875) | 2700 (2200‐6600) | .91 |
| Preoperative serum [K+] (mmol/L) | 4.3 (4.1‐4.7) | 3.9 (3.9‐4.7) | .78 |
| Preoperative serum [Na+] (mmol/L) | 137 (133‐141) | 137 (134‐141) | .28 |
| RBC transfusion (unit) | 3 (1.5‐7.5) | 3 (0.5‐8.5) | .86 |
Data are presented as median (interquartile range) or numbers (percentages).
DCD, donation after circulatory death, DBD, donation after brain death, MELD score, Model for End‐Stage Liver Disease score, RBC, Red Blood Cell.
a
Cold ischemia time was defined as the interval between start of aortic cold flush until start of DHOPE or in‐vivo graft reperfusion.
b
The time interval between the discontinuation of mechanical ventilation and the start of aortic cold flush in the donor (international donor warm ischemia time).
c
The time interval between cardiac arrest and the start of aortic cold flush in the donor.