Table 2.
Baseline demographics for the responder population (relapse and non‐relapse) in patients with plaque psoriasis (UNCOVER‐J)
| Characteristic | Relapse population (N = 61) | Non‐relapse population (N = 9) | Responder population total (N = 70) |
|---|---|---|---|
| Age, years | 43.8 (11.18) | 53.3 (9.27) | 45.1 (11.35) |
| Male, n (%) | 49 (80.3) | 7 (77.8) | 56 (80.0) |
| Weight, kg | 74.6 (16.66) | 65.6 (12.91) | 73.4 (16.43) |
| Duration of psoriasis symptoms, years | 15.5 (9.81) | 12.0 (9.11) | 15.0 (9.73) |
| Prior systemic therapy, n (%) | |||
| Non‐biologic only | 34 (55.7) | 6 (66.7) | 40 (57.1) |
| Biologic only | 1 (1.6) | 0 | 1 (1.4) |
| Non‐biologic and biologic | 12 (19.7) | 0 | 12 (17.1) |
| PASI score | 26.9 (9.02) | 24.2 (6.52) | 26.5 (8.75) |
| sPGA score | 3.8 (0.57) | 3.8 (0.44) | 3.8 (0.55) |
| Scalp psoriasis, n (%) | 60 (98.4) | 9 (100.0) | 69 (98.6) |
| PSSI score in patients with scalp psoriasis | 26.0 (15.66)† | 24.3 (14.50) | 25.8 (15.42)‡ |
| Nail psoriasis, n (%) | 32 (52.5) | 6 (66.7) | 38 (54.3) |
| NAPSI score in patients with nail psoriasis | 32.2 (22.27) | 36.2 (25.40) | 32.8 (22.47) |
| PsA, n (%) | 9 (14.8) | 1 (11.1) | 10 (14.3) |
| Pain VAS in patients with PsA | 63.2 (22.35) | 30.0 (NA) | 59.9 (23.55) |
| DLQI score | 11.3 (6.39) | 4.3 (2.35) | 10.4 (6.46) |
| Itch NRS score | 6.3 (2.58) | 4.6 (2.01) | 6.1 (2.57) |
†Baseline scores only available for 58 patients.
‡Baseline scores only available for 67 patients.
Data are mean (SD) unless otherwise stated. A total of 61/70 patients who entered the Treatment Withdrawal Period relapsed by Week 100.
DLQI, Dermatology Life Quality Index; NA, not applicable; NAPSI, Nail Psoriasis Severity Index; NRS, numeric rating scale; PASI, Psoriasis Area Severity Index; PsA, psoriatic arthritis; PSSI, Psoriasis Scalp Severity Index; SD, standard deviation; sPGA, Static Physician Global Assessment; VAS, visual analogue scale.