Table 1.
Summary of HCPs Identified in the Enriched CH1 Unbound Fraction
| Identified HCP | Description | Score† | Intensity* | Coverage (%) | Amino Acids |
|---|---|---|---|---|---|
| Cathepsin L | >gi|344,259,154|gb|EGW15258.1| | 465.6 | 6.13E+06 | 84 | 333 |
| Clusterin | >gi|344,249,681|gb|EGW05785.1| | 435.0 | 3.77E+06 | 40 | 447 |
| Metalloproteinase inhibitor 1 | >gi|344,258,664|gb|EGW14768.1| | 347.5 | 1.73E+06 | 41 | 203 |
| Inter‐alpha‐trypsin inhibitor heavy chain H5 | >gi|344,238,973|gb|EGV95076.1| | 228.1 | 2.75E+06 | 19 | 913 |
| Follistatin‐related protein 1 | >gi|344,236,558|gb|EGV92661.1| | 366.6 | 1.83E+06 | 22 | 583 |
| Sulfated glycoprotein 1 | >gi|344,242,104|gb|EGV98207.1| | 363.1 | 1.54E+06 | 36 | 249 |
| Glucose‐regulated protein | >gi|350,537,423|gb|NP_001233668.1| | 231.4 | 1.14E+06 | 15 | 654 |
| Amyloid beta A4 protein | >gi|344,251,481|gb|EGW07585.1| | 290.4 | 1.11E+06 | 15 | 433 |
| Cathepsin D | >gi|344,248,735|gb|EGW04839.1| | 203.9 | 4.42E+05 | 16 | 408 |
| Protein S100‐A11 | >gi|344,255,219|gb|EGW11323.1| | 236.5 | 8.26E+05 | 50 | 100 |
| Insulin‐like growth factor‐binding protein 4 | >gi|344,256,935|gb|EGW13039.1| | 213.2 | 1.02E+06 | 30 | 254 |
| Cornifin‐A | >gi|344,257,771|gb|EGW13875.1| | 286.4 | 4.64E+05 | 55 | 113 |
| Ganglioside GM2 activator | >gi|344,252,723|gb|EGW08827.1| | 228.3 | 5.80E+05 | 45 | 191 |
| Granulins | >gi|344,252,078|gb|EGW08182.1| | 201.7 | 2.05E+05 | 12.67 | 592 |
*
The total intensity is the sum of all fragment ion peak intensities from all MS/MS spectra.
†
The score reflects the quality of the match between the predicted and observed MS/MS peaks (peptide‐spectrum match). The score ranges from 0 to 1000. Only HCPs with score ≥200 are listed.