Table 1.
Absolute bias and RSD15% of the MWF estimation of healthy WM tissue and a WM lesion using the NNLS and OMP algorithms with varying SNR
| Healthy WM | WM lesion | ||||||
|---|---|---|---|---|---|---|---|
| NNLS | OMP | NNLS/OMP | NNLS | OMP | NNLS/OMP | ||
| SNR | |||||||
| Absolute bias | 100 | 6.4 | 3.9 | 1.6 | 2.9 | 2.1 | 1.4 |
| 200 | 4.4 | 2.5 | 1.8 | 1.7 | 1.3 | 1.3 | |
| 350 | 3.0 | 1.6 | 1.9 | 1.0 | 0.7 | 1.4 | |
| RSD15% | 100 | 57% | 49% | 1.2 | 34% | 31% | 1.1 |
| 200 | 29% | 32% | 0.9 | 17% | 20% | 0.9 | |
| 350 | 19% | 22% | 0.9 | 10% | 14% | 0.7 | |
Abbreviations: MWF, myelin water fraction; NNLS, nonnegative least squares; OMP, orthogonal matching pursuit; RSD, relative standard deviation; WM, white matter.