Figure 6.

Improvement of IBH severity score (ISI) by vaccination with eIL‐5‐CuMV_TT vaccine. A & B, All graphs include all horses, n = 30 (“Pre‐season”, “1st year”, “2nd year”), independent of antibody titer: ITT, intention to treat. ISI score with ISI 50 and ISI 75. ISI 50 includes % of horses that improved clinical lesion score by 50% and more, ISI 75 includes % of horses that improve clinical lesion score by 75% and more. A, ISI 50 (black) and ISI 75 (gray) score of “1st year” in the blinded study comparing vaccinated (V) and placebo‐treated (P) horses to “Pre‐season.” B, ISI 50 (black) and ISI 75 (gray) score of Group 1 (V1) and Group 2 (V2) horses of “2nd year” to “Pre‐season.” IBH, insect‐bite hypersensitivity