Fig. 4. Offspring acquire, via nursing, persistent protection from Nb related to raised T_H2 CD4 T cell responses following Nb infection in an allogeneic setting.

(A) Three-day-old NvM C57BL/6 pups were fostered on BALB/c NvM or WT NbM dams before being infected at 8 weeks old with 500 × Nb L3 and euthanized at day 5 PI. (B) Intestinal worm burdens at day 5 PI in 8-week-old mice born to either NvM or NbM were established. (C) Numbers of lung CD3⁺CD4⁺, ST2⁺, IL-13⁺, and CD44⁺CD62L_lo expressing T cell populations were quantified. All data are representative of a minimum of two experimental repeats. *P < 0.05, **P < 0.01, and ***P < 0.001.