Table 1.

Sarcoma botryoides of the uterine cervix in infant (reported cases since 1959).

Author	Patient age	Chief complaints	IHC	Treatment	Relapse	Therapy for Relapse	Outcome
Crawford (1959) [18]	11-month old	Growth in the perineal region in the past 3 months	Not stated	Surgery (total abdominal hysterectomy and colpectomy)	No		A&W*, 18 months
Kobi et al. (2009) [19]	1-year old	Not stated	Not stated	Surgery (no further explanation)	No		A&W*, 29 months
Kobi et al. (2009) [19]	2-year old	Not stated	Not stated	Surgery (no further explanation)	No		A&W*, 8 months
van Sambeeck et al. (2014) [2]	17-month old	Abnormal vaginal bleeding and vaginal tissue loss with a “grape bunch” appearance	Focal positivity for desmin and myogenin	Chemotherapy (VAI*** for 9 cycles)	Yes (6 months after chemotherapy)	Chemotherapy and brachytherapy (no further explanation)	A&W*, 12 months
Yasmin et al. (2015) [17]	7-month old	Protruding mass in the vaginal area for 7 days	Not stated	Surgery (subtotal hysterectomy) and chemotherapy (5 cycles, no explanation about the regiment)	Yes (2 months after chemotherapy)	Surgery and chemotherapy (no further explanation)	Not stated
ALSaleh et al. (2017) [20]	18-month old	Spontaneous intermittent painless vaginal bleeding in the past 10 months	Not stated	Neoadjuvant chemotherapy (VAC** for 10 cycles) → Surgery (total abdominal hysterectomy and bilateral salpingectomy with upper vaginectomy) → Chemotherapy (VAC** for 5 cycles)	No		A&W*, 12 months
Current study	3-year old	protruding mass from vagina for 7 months	Positive anti-desmin and anti-myogenin antibody	Tumor excision	Yes (3 months after tumor excision)	Surgery (Wide excision with safe margin of 1–2 cm) → Chemotherapy (VAC** for 6 cycles)	A&W*, 18 months

IHC – immunohistochemistry;

^*A&W – alive and well;

^**VAC – vincristine, actinomycin D, cyclophosphamide;

^***VAI – vincristine, actinomycin D, ifosfamid.