Common driver alterations in MDS and other myeloid neoplasms. (A) Frequencies of major driver mutations and CNAs are plotted, combining data from 7 publications,11,18,35-38,40 which include 1449 low- and 966 high-risk MDS, 46 MDS/MPN, 549 sAML, and 1540 primary AML (pAML) cases. Green bars indicate type I genes.36 (B) Odds ratios and their 95% confidence intervals (CIs) of frequencies of major driver mutations and CNAs between MDS (including MDS/MPN) and pAML are shown in forest plots.