Figure 5.

Relationship between crescent localization and refraction in children with Down syndrome vs. controls. Crescents (black lines) were evident in children with Down syndrome, without association with a specific refractive status. In controls, the crescents were more prevalent in those with myopia and astigmatism. Temporal crescents (red lines) were evident mostly in children with and without Down syndrome with myopia and myopic astigmatism. Crescents below the disc and annular crescents were more prevalent in children with Down syndrome (blue and purple lines). Other localizations (green lines) were rare.