Table 4.
Optic disc ovality and torsion and the presence of crescents, peripapillary atrophy and pigment anomalies in children with Down syndrome vs. controls.
| Parameter | Down syndrome | Controls | P-value | ||
|---|---|---|---|---|---|
| Right eye | Left eye | Right eye | Left eye | ||
| Optic disc ovality | 1.2 ± 0.20 (n = 48)a |
1.2 ± 0.22 (n = 47)a |
1.2 ± 0.12 (n = 52) |
1.2 ±0.13 (n = 52) |
0.92 |
| Optic disc torsion | 16 (32%) (n = 50) |
12 (24%) (n = 50) |
2 (3.8%) (n = 52) |
6 (11.5%) (n = 52) |
0.034 |
| Crescents present | 21(42%) (n = 50) |
21(42%) (n = 50) |
5 (9.6%) (n = 52) |
5 (9.6%) (n = 52) |
0.0002 |
| Peripapillary atrophy | 18 (36%) (n = 50) |
17 (34%) (n = 50) |
3 (5.8%) (n = 52) |
3 (5.8%) (n = 52) |
<0.05 |
| Peripapillary pigment anomalies | 17 (34%) (n = 50) |
17 (34%) (n = 50) |
2 (3.8%) (n = 52) |
2 (3.8) (n = 52) |
<0.0001 |
a
The vertical-to-horizontal disc diameter ratio was unavailable for five eyes of children with Down syndrome with overall elevated contour, making it impossible to differentiate the disc margins in a precise manner.