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. 2018 Oct 22;70(12):1923–1932. doi: 10.1002/art.40680

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© 2018 Eli Lilly and Company. Arthritis & Rheumatology published by Wiley Periodicals, Inc. on behalf of American College of Rheumatology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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B cell counts during treatment. Counts of CD19+ B cells (A), switched memory B cells (B), non‐switched memory B cells (C), mature naive B cells (D), and immature transitional B cells (E) are shown. Values are the median and 25th–75th percentiles. A includes patients with TE high B cell count and TE low B cell count. Values are the number (%) of the NAR. * = P ≤ 0.05; *** = P ≤ 0.001 versus placebo, based on the least squares mean difference change from baseline. See Figure 1 for definitions.