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Simplified signaling mechanisms of ligand‐gated ion channels (A) and G‐protein‐coupled receptors (B). If an agonist (represented by a triangle) binds to a channel, the channel opens and ions (represented by small diamonds) can enter the cell. If the agonist binds to a receptor, the G‐protein (represented by an ellipse) dissociates from the receptor complex and activates specific effector proteins
