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. 2018 Nov 18;39(3):1014–1052. doi: 10.1002/med.21552

Figure 2.

Figure 2

GPCR activation (left circuit, open arrows) and GTP cycle (right circuit, solid arrows). As in Figure 1, the agonist is represented by a triangle, the G‐protein by an ellipse and the receptor by a sinusoid line. The center of the figure shows the “ternary complex” consisting of agonist, receptor and G‐protein. GPCR, G‐protein‐coupled receptor; GTP, guanosine triphosphate