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Oligomerization‐dependent high‐affinity state. In this schematic representation, the receptors are drawn as homodimers. Most higher order G‐protein‐coupled receptor complexes are homodimers, heterodimers or tetramers consisting of two different homodimers. The high‐affinity state of the receptor is pictured as a sinusoid, the low‐affinity state as a compressed sinusoid, and the agonist as a triangle is pictured as a compressed sinusoid and the agonist as a triangle
