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. 2018 Nov 18;39(3):1014–1052. doi: 10.1002/med.21552

Figure A1.

Figure A1

Relationship between the fraction of ligand‐occupied receptors and B/F ratio. At equilibrium, B/B max = F/(F + K d), therefore B/F = B max/(F + K d). If FK d, then BB max and B/F ~ B max/K d. Note that at low concentrations (F/K d ≪ 1), the ligand occupies only a small part of total receptor population, and the B/F ratio (binding potential) is stable (left part of the graph)