Figure 6.

Detection of two mosaic deletions on chromosome 13. For this case, cfDNA‐based noninvasive prenatal testing (NIPT) indicated a possible partial or full monosomy 13, while chromosome analysis of chorionic villus sampling (CVS) tissue showed a normal male pregnancy. We retrieved three fetal trophoblastic cells of which two showed a normal chromosome 13 content (Panels A and B). The third fetal cell, however, showed two small deletions of 4 Mb and 2.6 Mb (Panel C). The normal CVS chromosomal microarray (CMA) result for chromosome 13 is shown in Panel D [Colour figure can be viewed at wileyonlinelibrary.com]