Table 5.
Topology metrics | Healthy controls (mean ± std) | Schizophrenia patients (mean ±, std) | p-value | |
---|---|---|---|---|
Proposed method | Connectivity strength | 32.3520 ± 1.6443 | 31.5238 ± 1.5095 | 0.0430* |
Average degree | 87.0486 ± 0.9023 | 86.5014 ± 1.2570 | 0.0323* | |
Density | 0.9781 ± 0.0101 | 0.9719 ± 0.0141 | 0.0323* | |
Clustering coefficient | 0.9802 ± 0.0083 | 0.9755 ± 0.0102 | 0.0295* | |
Characteristic path length | 1.0219 ± 0.0101 | 1.0281 ± 0.0141 | 0.0323* | |
global efficiency | 0.9890 ± 0.0051 | 0.9860 ± 0.0071 | 0.0323* | |
Local efficiency | 0.9901 ± 0.0042 | 0.9877 ± 0.0051 | 0.0295* | |
Closeness centrality | 88.0243 ± 0.4511 | 87.7507 ± 0.6285 | 0.0323* | |
Edge betweenness centrality | 1.0451 ± 0.0213 | 1.0582 ± 0.0309 | 0.0338* | |
Node betweenness centrality | 1.9514 ± 0.9023 | 2.4986 ± 1.2570 | 0.0323* | |
Radiality | 1.9781 ± 0.0101 | 1.9719 ± 0.0141 | 0.0323* | |
Assortativity | −0.1272 ± 0.0447 | −0.1515 ± 0.0385 | 0.0124* | |
Structural consistency | 0.9580 ± 0.0053 | 0.9613 ± 0.0050 | 0.0058* | |
Fitted exponent of power-law degree distribution | 8.4238 ± 0.0879 | 8.4868 ± 0.1182 | 0.0203* | |
Pearson based method | Connectivity strength | 32.4749 ± 1.8836 | 31.5293 ± 1.5712 | 0.0893 |
Average degree | 88.7153 ± 0.0663 | 88.6889 ± 0.0570 | 0.5642 | |
Density | 0.9968 ± 7.4499e−4 | 0.9969 ± 6.4031e−4 | 0.5642 | |
Clustering coefficient | 0.9968 ± 7.5481e−4 | 0.9969 ± 6.4794e−4 | 0.5630 | |
Characteristic path length | 1.0032 ± 7.4499e−4 | 1.0031 ± 6.4031e−4 | 0.5642 | |
Global efficiency | 0.9984 ± 3.7249e−4 | 0.9984 ± 3.2016e−4 | 0.5642 | |
Local efficiency | 0.9984 ± 3.7740e−4 | 0.9984 ± 3.2397e−4 | 0.5630 | |
Closeness centrality | 88.8576 ± 0.0332 | 88.8620 ± 0.0285 | 0.5642 | |
Edge betweenness centrality | 1.0064 ± 0.0015 | 1.0062 ± 0.0013 | 0.5636 | |
Node betweenness centrality | 0.2847 ± 0.0663 | 0.2759 ± 0.0570 | 0.5642 | |
Radiality | 1.9968 ± 7.4499e−4 | 1.9969 ± 6.4031e−4 | 0.5642 | |
Assortativity | −0.0195 ± 7.6192e−4 | −0.0196 ± 6.5486e−4 | 0.5642 | |
Structural consistency | 0.9700 ± 0.0068 | 0.9709 ± 0.0058 | 0.5621 | |
Fitted exponent of power-law degree distribution | 8.3573 ± 3.5527e−15 | 8.3573 ± 1.7764e−15 | NaN |
The asterisk (*) denotes the statistically significant differences (p < 0.05).