Table 3.
Risk of bias of the clinical trials.
| Compounds/formula | A | B | C | D | E | F | G | H | Reference |
|---|---|---|---|---|---|---|---|---|---|
| JTTZ Formula | ? | – | – | – | + | + | ? | ? | (Yu X. et al., 2018) |
| Tangyiping Granules (TYP) | + | + | + | + | ? | + | ? | ? | (Huang et al., 2016) |
| Jinlida (JLD) | + | – | – | – | ? | + | ? | ? | (Shi et al., 2016) |
| Qingxue Dan (QXD) | + | ? | + | + | – | + | ? | ? | (Chung et al., 2016) |
| Artemisia dracunculus | ? | – | + | + | – | + | ? | ? | (Mendez-Del Villar et al., 2016) |
| Qingre Yangyin Recipe (QRYYR) | – | – | + | – | – | – | ? | ? | (Zhang, 2015) |
| Sancaijiangtang powders | + | – | + | – | – | + | ? | ? | (Qiang et al., 2015) |
| Cinnamon | + | ? | + | + | + | + | ? | ? | (Mirfeizi et al., 2016) |
| Jinlida | + | + | + | + | + | + | – | ? | (Lian et al., 2015) |
| Zhenggan Tang decoction | + | – | – | – | – | + | ? | ? | (Xu et al., 2015) |
| Marjoram tea | + | – | + | + | + | + | ? | ? | (Haj-Husein et al., 2016) |
| xin-ju-xiao-gao-fang (XJXGF) | + | – | + | + | – | + | ? | ? | (Zhou et al., 2014) |
| Yiqi Huaju Recipe (YHR) | + | – | + | – | – | + | ? | ? | (Chen et al., 2014) |
| Ginger (GG) | + | – | + | + | ? | + | ? | ? | (Mozaffari-Khosravi et al., 2014) |
| Curcumin | + | + | + | + | – | + | ? | ? | (Chuengsamarn et al., 2014) |
| Hydroalcoholic extract of Juglans regia (walnut) leaves | + | + | + | + | – | + | ? | ? | (Rabiei et al., 2018) |
| Yangxin Tongmai Formula (YTF)1 | – | – | – | – | – | + | ? | ? | (Luo et al., 2018) |
| Sancai powder | + | – | + | – | – | + | ? | ? | (Guo et al., 2016) |
| Fraxinus excelsior L. seeds/fruits extract | ? | + | + | + | + | + | ? | ? | (Zulet et al., 2014) |
| Berberine | + | ? | + | + | – | + | ? | ? | (Perez-Rubio et al., 2013) |
| Aloe vera gel complex | + | – | + | + | – | + | ? | ? | (Choi et al., 2013) |
| Green tea extract | + | ? | + | + | – | + | ? | ? | (Liu C. et al., 2014) |
| Cinnamon | + | – | + | + | – | + | ? | ? | (Askari et al., 2014) |
| Soybean leaf extracts (SLEs) | + | – | – | – | – | + | ? | ? | (Choi et al., 2014) |
| Nigella sativa | + | – | + | – | – | + | ? | + | (Kaatabi et al., 2015) |
| Chamomile tea | + | – | + | – | – | + | ? | ? | (Rafraf et al., 2015) |
| DLBS3233 | ? | – | + | + | – | + | ? | ? | (Manaf et al., 2016) |
| Garlic extract | ? | – | + | + | – | + | ? | ? | (Atkin et al., 2016) |
| Bee propolis | ? | – | + | + | – | + | ? | ? | (Samadi et al., 2017) |
| Artemisia Extract | + | – | + | + | – | + | ? | ? | (Sun X. et al., 2016) |
| Red wine polyphenols | + | – | + | + | – | + | ? | ? | (Woerdeman et al., 2018) |
| Fresh yellow onion | + | – | + | + | + | + | ? | ? | (Jafarpour-Sadegh et al., 2017) |
| Gymnema sylvestre | + | – | + | + | – | + | ? | ? | (Zuniga et al., 2017) |
| Artichoke leaf extract | + | – | + | + | – | + | ? | ? | (Ebrahimi-Mameghani et al., 2018) |
| Silybum marianum (L). Gaertn. (silymarin) extract | + | – | + | + | – | + | ? | ? | (Ebrahimpour-Koujan et al., 2018) |
| Green coffee extract | + | + | + | + | ? | + | ? | ? | (Roshan et al., 2018) |
A, Adequate sequence generation; B, Concealment of allocation; C, Blinding (patient); D, Blinding (investigator); E, Blinding (assessor); F, Incomplete outcome data addressed (ITT analysis); G, Free of selective reporting; H, Other potential threat to validity; +, Low risk; –, High risk; ?, Unclear.