Table 2.
Cardiac serum biomarker and CMR measures in study participants with significant arrhythmias compared with those without significant arrhythmias
| Significant arrhythmia on ILR (n = 8) | No significant arrhythmia on ILR (n = 11) | Mean difference (95% CI) | |
|---|---|---|---|
| Cardiac serum biomarkers | |||
| hs-TnI, ng/l | 141 (184) | 23 (51) | 117 (−11, 245) |
| NT-proBNP, ng/l | 198 (128) | 106 (122) | 92 (−30, 215) |
| CK, IU/l | 152 (162) | 133 (145) | 19 (−138, 176) |
| CMR (n = 15) | |||
| LGE present (n = 5) | 1 (7) | 4 (29) | |
| LGE not present (n = 9) | 4 (29) | 5 (36) | |
| ECV (n = 14) | 32 (2) | 29 (4) | 2 (−2, 6) |
| MPR (n = 12) | 1.9 (0.4) | 2.1 (1.2) | −0.2 (−1.3, 0.8) |
| LVEF | 62 (4) | 59 (5) | 2 (−3, 8) |
| LV mass/BSA, g/m2 | 46 (7) | 44 (14) | 2 (−10, 15) |
Mean (s.d.) values are shown unless stated otherwise. 15/19 patients had CMR performed. Of these 15 with a CMR, LGE and ECV data could be obtained from 14, and perfusion data from 12. BSA: body surface area; CK: creatine kinase; CMR: cardiovascular magnetic resonance; ECV: extracellular-volume fraction; hs-TnI: high-sensitivity troponin I; ILR: implantable loop recorder; LGE: late gadolinium enhancement; LV: left ventricular; LVEF: left ventricular ejection fraction; MPR: myocardial perfusion reserve; NT-proBNP: N-terminal pro-brain natriuretic peptide.