Table 2.

Normalized expression values of indicated transcripts in early arthritis patient diagnostic groups of the independent cohort

Gene			Normalized expressiona
Symbol	RefSeq	Illumina Probe ID	RA (n = 47)	Non-RA (n = 114)	Fold-changeb	P-valuec
BCL3	NM_005178	ILMN_1710514	867	585	1.48	<0.001
PIM1	NM_002648	ILMN_1815023	3567	2633	1.35	<0.001
SOCS3	NM_003955	ILMN_1781001	850	614	1.38	0.004
LDHA	NM_005566	ILMN_1807106	7493	6572	1.14	<0.001
GPRIN3	CR743148d	ILMN_1901616	377	322	1.17	0.004
MUC1	NM_001044391	ILMN_1756992	310	283	1.10	0.013
PDCD1	NM_005018	ILMN_1806725	168	159	1.06	0.029
SBNO2	NM_014963	ILMN_1808811	193	180	1.07	0.011
IGFL2	NM_001002915	ILMN_1790227	142	135	1.05	0.017
LOC731186	XM_001128760	ILMN_1900154	148	145	1.02	0.033
CMAHP	NR_002174	ILMN_1704084	222	217	1.02	ns
NOG	NM_005450	ILMN_1652287	143	150	−1.05	0.007

RefSeq accession numbers and Illumina probe IDs are given (see supplementary Table S1, available at Rheumatology online for probe sequences).

^aMedian normalized gene expression values presented.

^bLinearized fold-change relative to non-RA group given.

^cMann–Whitney U test.

^dTranscript CR743148 has been retired from the National Center for Biotechnology Information, but the expressed sequence tag corresponds to splice variant(s) within the GPRIN3 gene (chromosome 4.90). Genes demonstrating >1.2-fold differences indicated in boldface. ns: not significant.