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. 2019 Jun 18;7:e7025. doi: 10.7717/peerj.7025

Figure 2. Experimental validation of the top 6 over- and underexpressed messenger RNAs (mRNAs).

Figure 2

The change in circulating mRNA levels of collagen type VI alpha 3 chain (COL6A3) (A), serpin family H member 1 (SERPINH1) (B), pleckstrin homology and RhoGEF domain containing G1 (PLEKHG1) (C), pepsinogen 4, group I (pepsinogen A) (PGA4) (D), potassium voltage-gated channel subfamily E regulatory subunit 2 (KCNE2) (E) and gastric intrinsic factor (GIF) (F) between gastric cancer patients and normal subjects detected by qPCR using Student’s t test. The Mann–Whitney U test was used to compare the expression status of circulating mRNAs in normal and GC groups. Data was shown as box plots and the intersecting line represents the median value with the interquartile range. Results were shown with means ± SEM. *p < 0.05, **p < 0.01.