Table 1.
Technology characteristics of the four immunochemical methods that were used to quantify CSF α‐synuclein
| Roche | MSD | BioLegend | ADx | |
|---|---|---|---|---|
| Technology | ||||
| Sandwich immunoassay | + | + | + | + |
| Detection | ECL | ECL | Luminescence | Absorbance‐based |
| Automation | + | − | − | − |
| Antibodies | ||||
| Capture antibody (epitope) | No information | No information | aSyn (118–122) | ADx301 (no information) |
| Detector mAb (epitope) | No information | No information | aSyn (103–108) | ADx302 (no information) |
| Calibrator | ||||
| Type | Recombinant | Recombinant | Recombinant | Recombinant |
ECL = electrochemiluminescence; rec. = recombinant.