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. Author manuscript; available in PMC: 2019 Jun 21.
Published in final edited form as: Expert Rev Vaccines. 2018 Jan 19;17(2):127–144. doi: 10.1080/14760584.2018.1425619

Figure 1. Antigenic sites on HIV-1 Envelope targeted by bNAbs.

Figure 1.

Shown are binding locations for bNAbs to the CD4-binding site; to a high-mannose-patch referred to as the V3 glycan supersite; to the V2 apex; and to the gp41 membrane proximal external region (MPER) of HIV-1 Envelope. bNAbs associated with each of these determinants are listed. This figure is adapted from Burton and Mascola, 2015 [157].