Table 2.
Simulation study for linear regression in Section 4.2 with n = 500 and, where applicable, the external study has sample size N = 300 and 2 replicates, while β0 = 0, β1 = 0.75. The target parameter, Θ = (θ1, …, θ5)T, where θj is the parameter for the jth category. Displayed are results for the estimation of θ5 − θ1. Ext-Int Data is the case that external data are used to estimate the measurement error variance. Int Data is the case that the internal data have 2 replicates, and the Ignore ME estimator ignores the measurement error and is based on the mean of these replicates. Coverage is the coverage rate of nominal 95% confidence intervals. RMSE is the square root of the mean squared error.
Results Analysis (θ5 − θ1) | ||||||
---|---|---|---|---|---|---|
Data | Method | mean bias | Mean Estimated Std. Err. | Actual Standard Deviation | RMSE | Coverage |
Homoscedastic ϵ ~ N(0, 1) | ||||||
X observed | 0.004 | 0.145 | 0.150 | 0.150 | 95.1% | |
Ext-Int Data | ||||||
Our Method | 0.013 | 0.249 | 0.233 | 0.233 | 95.8% | |
Ignore ME | −0.814 | 0.139 | 0.142 | 0.826 | 0.1% | |
Int Data | ||||||
Our method | −0.007 | 0.176 | 0.170 | 0.170 | 95.3% | |
Ignore ME | −0.536 | 0.142 | 0.145 | 0.555 | 3.7% | |
Heteroscedastic ϵ ~ N(0,0.2 + 0.5x2) | ||||||
X observed | 0.004 | 0.123 | 0.169 | 0.169 | 85.3% | |
Ext-Int Data | ||||||
Our Method | 0.011 | 0.261 | 0.245 | 0.245 | 95.9% | |
Ignore ME | −0.814 | 0.122 | 0.135 | 0.825 | 0.1% | |
Int Data | ||||||
Our Method | −0.010 | 0.197 | 0.189 | 0.189 | 95.9% | |
Ignore ME | −0.537 | 0.123 | 0.141 | 0.555 | 1.8% |