TABLE I.
Statistical analysis of baseline data
| Characteristic | Patient group | p Valuea | ||
|---|---|---|---|---|
|
| ||||
| Overall | White | Asian American | ||
| Patients (n) | 58,780 | 54,827 | 3,953 | |
|
| ||||
| Age at diagnosis (years) | <0.001 | |||
| Median | 34 | 33 | 42 | |
| Range | 6–104 | 6–104 | 13–97 | |
|
| ||||
| Age group at diagnosis [n (%)] | ||||
| <25 Years | 8770 (14.9) | 8573 (15.6) | 197 (5.0) | |
| 25–45 Years | 36195 (61.6) | 34194 (62.4) | 2001 (50.6) | |
| 45–60 Years | 8554 (14.6) | 7506 (13.7) | 1048 (26.5) | |
| >60 Years | 5260 (8.9) | 4554 (8.3) | 706 (17.9) | |
| Unknown | 1 (0.0) | 0 (0.0) | 1 (0.0) | |
|
| ||||
| FIGO stage (1994) [n (%)] | <0.001 | |||
| In situ | 40860 (69.6) | 38985 (71.1) | 1875 (47.4) | |
| I | 11122 (18.9) | 9908 (18.0) | 1214 (30.7) | |
| II | 3078 (5.2) | 2620 (4.8) | 458 (11.6) | |
| III | 1954 (3.3) | 1683 (3.1) | 271 (6.9) | |
| IV | 1006 (1.7) | 925 (1.7) | 81 (2.0) | |
| Unknown | 760 (1.3) | 706 (1.3) | 54 (1.40) | |
|
| ||||
| Lymph node metastasis [n (%)] | <0.001 | |||
| None | 52310 (89.0) | 49041 (89.5) | 3269 (82.7) | |
| Regional | 2091 (3.5) | 1821 (3.3) | 270 (6.8) | |
| Distant | 507 (0.9) | 444 (0.8) | 63 (1.6) | |
| Unknown | 3872 (6.6) | 3521 (6.4) | 351 (8.9) | |
|
| ||||
| Registry area [n (%)] | <0.001 | |||
| Middle | 20263 (34.5) | 20034 (36.6) | 229 (5.8) | |
| Eastern | 16514 (28.1) | 16239 (29.6) | 275 (6.9) | |
| Western | 22003 (37.4) | 18554 (33.8) | 3449 (87.3) | |
|
| ||||
| Marital status [n (%)] | <0.001 | |||
| Single or other | 14323 (24.4) | 13651 (24.9) | 672 (17.0) | |
| Married | 35552 (60.5) | 32616 (59.5) | 2936 (74.3) | |
| Unknown | 8905 (15.1) | 8560 (15.6) | 345 (8.7) | |
|
| ||||
| Primary site [n (%)] | <0.001 | |||
| Endocervix | 4742 (8.1) | 4321 (7.8) | 421 (10.7) | |
| Exocervix | 3103 (5.3) | 2992 (5.5) | 111 (2.8) | |
| Overlapping lesions | 1610 (2.7) | 1538 (2.8) | 72 (1.8) | |
| Cervix uteri | 49325 (83.9) | 45976 (83.9) | 3349 (84.7) | |
|
| ||||
| Grade [n (%)] | 0.132 | |||
| Well differentiated | 1764 (3.0) | 1579 (2.8) | 185 (4.7) | |
| Moderately differentiated | 4930 (8.4) | 4309 (7.9) | 621 (15.7) | |
| Poorly differentiated | 4856 (8.2) | 4258 (7.8) | 598 (15.1) | |
| Undifferentiated | 500 (0.9) | 439 (0.8) | 61 (1.5) | |
| Unknown | 46730 (79.5) | 44242 (80.7) | 2488 (63.0) | |
|
| ||||
| Histology [n (%)] | <0.001 | |||
| Squamous cell | 38960 (66.3) | 36415 (66.5) | 2545 (64.4) | |
| Adenocarcinoma | 4506 (7.7) | 4026 (7.3) | 480 (12.1) | |
| Adenosquamous | 794 (1.3) | 712 (1.3) | 82 (2.1) | |
| Others | 140 (24.7) | 13674 (24.9) | 846 (21.4) | |
|
| ||||
| Tumour diameter [n (%)] | <0.001 | |||
| <7 mm | 8579 (14.6) | 8165 (14.9) | 414 (10.5) | |
| 7 mm–4 cm | 3850 (6.5) | 3300 (6.0) | 550 (13.9) | |
| >4 cm | 3319 (5.6) | 2885 (5.3) | 434 (11.0) | |
| Unknown | 43032 (73.3) | 40477 (73.8) | 2555 (64.6) | |
|
| ||||
| Radiation [n (%)] | <0.001 | |||
| No | 49970 (85.0) | 47152 (86.0) | 2818 (71.3) | |
| Yes | 8646 (14.7) | 7528 (13.7) | 1118 (28.3) | |
| Unknown | 164 (0.3) | 147 (0.3) | 17 (0.4) | |
|
| ||||
| Surgery [n (%)] | <0.001 | |||
| No | 10282 (17.5) | 9382 (17.1) | 900 (22.8) | |
| Yes | 48436 (82.4) | 45390 (82.8) | 3046 (77.0) | |
| Unknown | 62 (0.1) | 55 (0.1) | 7 (0.2) | |
a
By chi-square test; does not include the “Unknown” category.