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. Author manuscript; available in PMC: 2019 Jun 21.
Published in final edited form as: Cogent Med. 2017 Apr 26;4(1):1317690.

Figure 5. BPS-induces significant increases in mature ovarian follicles.

Figure 5

A) H&E staining of an ovary collected at PND22. Examples of ovarian follicles at various stages of development are indicated. Photomicrographs were collected with a 10× EpiPlan Objective. B) BPS exposure induced significant increases in the number of secondary follicles in the entire ovary. C) The total number of follicles through the entire ovary was increased in BPS-treated females, although this increase was not statistically significant. D) To account for differences in ovarian size, four sections from the middle of the ovary were used to quantify follicle numbers in the various stages of development. BPS induced significant increases in the number of secondary follicles and non-significant increases in the number of primary and antral follicles. E) Non-significant increases were observed in total number of measured in four ovarian sections from BPS-treated ovaries. In all panels, * indicates p<0.05, independent samples t-test. In all groups, n=5 per treatment.