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. 2019 Jun 21;14(6):e0214832. doi: 10.1371/journal.pone.0214832

Table 5. One way antigenic relationship (r1-value) of the outbreak and carrier virus isolates with the currently used vaccine strain, O/IND/R2/1975, as determined by 2D-VNT assay.

Values are expressed as mean± standard deviation (s.d). Values <0.3 are in bold, indicating poor vaccine protection against that isolate.

Animal ID Date of virus isolation
Acute Phase (Jan’ 2014) March 2014 May 2014 Aug’ 2014 Nov’ 2014 Feb’ 2015
Clinical virus isolates
C6670 0.6±0.04
C5636 0.6±0.08
Carrier virus
CC12517 0.33±0.017 0.522±0.102
CC5143 0.78±0.091
CC20252 0.32±0.016
CC20213 0.36±0.050 0.41±0.061
CC5173 0.21±0.020
CC458 0.42±0.050
CC5430 0.6±0.111
CC20453 0.45±0.087
CC20216 0.42±0.071
CC6636 0.66±0.131
CC6646 0.26±0.034
CB16403 0.66±0.144 0.21±0.047
CB1964 0.41±0.051 0.383±0.060 0.396±0.064 0.173±0.05
CB2224 0.33±0.025 0.22±0.011
CB1908 0.33±0.038
CB1854 0.33±0.025 0.143±0.030 0.277±0.023
CB1760 0.42±0.058
CB6666 0.42±0.087
CB2036 0.16±0.011
CB1816 0.122±0.005 0.213±0.017
CB1973 0.11±0.017
CB2067 0.271±0.020
SC3595 0.49±0.102 0.295±0.007
SC3512 0.33±0.02
SC3568 0.23±0.015 0.819±0.095
SC3035 0.66±0.072
SB1932 0.229±0.030
SB1961 0.117±0.020
SB2017 0.248±0.025
SB1765 0.247±0.020

C, Clinically infected; CC, Convalescent cattle; CB, Convalescent buffalo; SC, Subclinical cattle; SB: Subclinical buffalo.