Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Time profile of the total fumarate concentration in tumor slices along the y-axis. (a) Control with no inhibition (black), (b) complete inhibition of GAPDH (purple), (c) complete inhibition of OXPHOS (grey) and (d) complete inhibition of ASCT2 (teal). Each time profile is an average of 30 iterations of model simulations with the reaction velocity, Vf, of the targeted reaction set equal to zero in each case.
