Table 1: Mexiletine QTc trial outcomes.
Genetic Variants |
baseline QTc |
Measured post mex QTc |
Predicted post mex QTc |
Prediction lower bound |
Prediction upper bound |
---|---|---|---|---|---|
F1473S | 550 | 491 | 488 | 449 | 526 |
I1768V | 520 | 503 | 499 | 462 | 520 |
K1500del | 478 | 434 | 415 | 381 | 449 |
K1500del | 500 | 430 | 434 | 399 | 469 |
K1500del | 493 | 463 | 428 | 393 | 463 |
K1500del | 494 | 434 | 429 | 394 | 463 |
L1608P | 604 | 480 | 518 | 477 | 558 |
N1774D | 814 | 610 | 750 | 693 | 807 |