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. Author manuscript; available in PMC: 2020 Feb 15.
Published in final edited form as: Circ Res. 2019 Feb 15;124(4):539–552. doi: 10.1161/CIRCRESAHA.118.314050

Table 1: Mexiletine QTc trial outcomes.

7 out of 8 patients have clinical measured QTc post mexiletine that fall into the predicted range.

Genetic
Variants
baseline
QTc
Measured
post mex
QTc
Predicted
post mex
QTc
Prediction
lower
bound
Prediction
upper
bound
F1473S 550 491 488 449 526
I1768V 520 503 499 462 520
K1500del 478 434 415 381 449
K1500del 500 430 434 399 469
K1500del 493 463 428 393 463
K1500del 494 434 429 394 463
L1608P 604 480 518 477 558
N1774D 814 610 750 693 807