Table 1.
Selected demographic variables by case-control status by study
| Discovery | Validation | |||||
|---|---|---|---|---|---|---|
| Case | Control | P-value* | Case | Control | P-value* | |
| (N=134) | (N=57) | (N=224) | (N=81) | |||
| Age, mean(SD) | 51.1(12.0) | 51.1(6.7) | 0.990 | 50.6(10.7) | 58.4(14.8) | <0.001 |
| BMI, mean(SD) | 31.1(6.2) | 30.4(7.0) | 0.499 | 32.8(7.7) | 33.4(8.3) | 0.599 |
| BMI category N(%) | ||||||
| normal(<25) | 18(13.43) | 17(29.82) | 28(12.11) | 10(12.35) | ||
| overweight(25–<3 0) | 45(33.58) | 15(26.32) | 63(28.25) | 26(32.10) | ||
| obese(30+) | 71(52.99) | 25(43.86) | 0.027 | 133(59.64) | 45(55.56) | 0.790 |
| Race | ||||||
| African Americans | 57(42.54) | 19(33.33) | 93(41.52) | 57(70.37) | ||
| Hispanic | 77(57.46) | 38(66.67) | 0.234 | 131(58.48) | 24(29.63) | <0.001 |
| Family history of breast cancer | ||||||
| 0 | 113(84.33) | 50(87.72) | 195(87.05) | 70(86.42) | ||
| 1 | 21(15.67) | 7(12.28) | 0.544 | 29(12.95) | 11(13.58) | 0.885 |
| ER | ||||||
| positive | 100(74.63) | 157(70.09) | ||||
| negative | 34(25.37) | 67(29.92) | ||||
| PR | ||||||
| positive | 77(57.46) | 134(59.82) | ||||
| negative | 57(42.54) | 90(40.18) | ||||
| HER2 | ||||||
| positive | 30(22.38) | 35(15.63) | ||||
| negative | 104(77.61) | 189(84.37) | ||||
| Stage | ||||||
| I | 44(32.83) | 72(32.14) | ||||
| II | 44(32.83) | 90(40.18) | ||||
| III & IV | 46(34.33) | 62(27.68) | ||||
*
Student T test was used to calculate the P value for continuous variables; and Chi square was used to calculate the P value for categorical variables.