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. Author manuscript; available in PMC: 2019 Sep 20.
Published in final edited form as: Annu Rev Biochem. 2019 Mar 18;88:725–783. doi: 10.1146/annurev-biochem-062917-011901

Figure 5.

Figure 5

Structures of nucleoporins in the CNC. A schematic of the NPC is shown in the top right corner, with the region of the NPC in which these nucleoporins are found colored in yellow. Crystal structures of scSeh1–scNup85 (PDB 3F3F), scSec13–scNup145C–scNup84 (PDB 3IKO), Nup107–Nup133 (PDB 3I4R), spNup120–spNup37 (PDB 4FHN), Nup133 (PDB 1XKS), mmELYS (PDB 4I0O), and Nup43 (PDB 4I79) are shown in ribbon representation (64, 68, 70, 71, 73, 97). Abbreviations: ALPS, amphipathic lipid packing sensor; CNC, coat nucleoporin complex; DIM, domain invasion motif; NPC, nuclear pore complex; PDB, Protein Data Bank.