Figure 1.
Mycobacterium tuberculosis folate pathway. Canonical pathway enzyme (green): DHPS: dihydropteroate synthase, DHFS: dihydrofolate synthase, DHFR: dihydrofolate reductase, TS: thymidylate synthase, SHMT: serine hydroxyl methyltransferase; Alternate pathway enzymes (orange) FDTS: flavin-dependent thymidylate synthase, Rv2671