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Top Left: Mtb DHFR in complex with NADPH (dark grey) and UCP1172 (light grey) at 1.4 Å (PDB ID: 6DDP); Top Right: Mtb DHFR in complex with NADPH and UCP1175 (yellow) at 1.7 Å (PDB ID: 6DDS); Middle Left: Mtb DHFR in complex with NADPH and PAS-M (brown) at 1.4 Å (PDB ID: 6DDW); Middle Right: Hu DHFR in complex with NADPH and UCP1172 (light grey) at 2.4 α (PDB ID: 6DE4); Bottom: Mtb Rv2671 in complex with NADPH and UCP1063 (cyan)
