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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Free Radic Biol Med. 2018 Dec 26;134:1–8. doi: 10.1016/j.freeradbiomed.2018.12.029

Fig. 3.

Fig. 3.

Bilateral H1-MRS scans of hippocampus revealed a large decrease in the Cho/Cr ratio in the Dox-treated WT group compared to saline control mice (****p<0.0001). Dox administration to TNFKO mice resulted in rebound of the hippocampal Cho/Cr ratio over that of Dox-treated WT mice (***p=0.0002), although there also was a significant difference in the Cho/Cr ratio in mice hippocampus of TNFKO mice between saline and Dox treatment groups (****P<0.0001). (n=6 and 5 individual animals of the WT and TNFKO groups, respectively).