KEY RESOURCES TABLE
| REAGENT or RESOURCE | SOURCE | IDENTIFIER |
|---|---|---|
| Antibodies | ||
| RPRD1B (Rabbit) | Bethyl | AB_11218400 |
| RPRD1B (Mouse) | Novus | AB_2285416 |
| RRPD1A | Santa Cruz | sc514724 |
| Pol II (8WG16) | Abcam | AB_306327 |
| Pol II (4H8) | Abcam | AB_304868 |
| Pol II (H224) | Santa Cruz | AB_2268548 |
| Pol II (K7ac) | This Paper | N/A |
| RPAP3 | Bethyl | AB_2621049 |
| HA (Rat) | Sigma | AB_10094468 |
| HA Agarose Bead | Sigma | AB_257974 |
| HA Magnetic Bead | Sigma | AB_2749815 |
| Normal IgG (Rabbit) | Santa Cruz | AB_737197 |
| Normal IgG (Mouse) | Santa Cruz | AB_737182 |
| HSP90 | Abcam | AB_444729 |
| HDAC1 | Abcam | AB_2264059 |
| AffiniPure Goat Anti-Mouse HRP | Jackson Immunoresearch | AB_10015289 |
| AffiniPure Goat Anti-Rabbit HRP | Jackson Immunoresearch | AB_2313567 |
| AffiniPure Goat Anti-Rat HRP | Jackson Immunoresearch | AB_2338128 |
| Chemicals, Peptides, and Recombinant Proteins | ||
| Panobinostat | Santa Cruz | CAS 404950-80-7 |
| Nicotinamide | Sigma | CAS 98-92-0 |
| α-Amanitin | Santa Cruz | CAS 23109-05-9 |
| CTD Peptides | Peptide 2.0 | N/A |
| Critical Commercial Assays | ||
| QIAquick PCR Purification Kit | Qiagen | 28104 |
| RNeasy Plus Mini Kit | Qiagen | 74136 |
| Ovation Ultralow System V2 | NuGEN | 0344-32 |
| Deposited Data | ||
| RNA Pol II ChIP-seq Data | GEO | GSE124996 |
| RNA Seq Data | GEO | GSE125486 |
| Western Blotting Data | Mendeley Data | DOI: 10.17632/f6w4wzb9dr.1 |
| Structural Modeling | Mendeley Data | DOI: 10.17632/f6w4wzb9dr.1 |
| SILAC Data | This Paper | Table S1 |
| Experimental Models: Cell Lines | ||
| NIH3T3 | ATCC | CRL-1658 |
| 293T | ATCC | CRL-3216 |
| Software and Algorithms | ||
| Skewer v 0.1.124 | Jiang et al., 2014 | N/A |
| Bowtie v 1.1.2 | Langmead et al., 2009 | N/A |
| MACS2 v 2.1.0.20150731 | Zhang et al., 2008 | N/A |
| DeepTools v 2.2.3 | Ramirez et al., 2016 | N/A |
| MaxQuant v 1.2.5.8 | Cox and Mann, 2008 | N/A |