Table 2.
The univariate and multivariate PerMANOVA analysis of the association between overall microbiome diversity and demographic and clinical variables
| PerMANOVA test* |
||
|---|---|---|
| Variables | univariate | multivariate |
| Maternal variables | ||
| Ethnicity | 0.065 | |
| Maternal age | 0.57 | |
| Education1 | 0.25 | |
| Marital status | 0.10 | |
| Obesity | 0.17 | |
| Preeclampsia | 0.99 | |
| Offspring variables | ||
| Gender | 0.485 | |
| Preterm | 0.65 | |
| Birth weight | 0.64 | |
| Meconium collection time | 0.33 | |
| Mode of delivery (C-section vs. vaginal) | 0.033 | 0.009 |
| NICU admission | 0.72 | |
| Antenatal Stress | ||
| Prenatal depression | 0.30 | |
| State anxiety | 0.55 | |
| Trait anxiety | 0.14 | |
| Pregnancy-related anxiety (total) | 0.001 | 0.001 |
| Fear of having handicapped child | 0.24 | |
| Fear of appearance change | 0.003 | 0.45 |
| Fear of birth/delivery | 0.005 | 0.39 |
| Perceived stress | 0.44 | |
| Stressful Life events-total | 0.45 | |
| Life experiences-partner | 0.72 | |
| Life experiences-health | 0.24 | |
| Life experiences-legal | 0.56 | |
| Life experiences-work/finance | 0.45 | |
| Life experiences-friend | 0.41 | |
*
PerMANOVA test was performed at genus level.