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. Author manuscript; available in PMC: 2020 Jun 21.
Published before final editing as: AIDS. 2018 Dec 21:10.1097/QAD.0000000000002125. doi: 10.1097/QAD.0000000000002125

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Inclusion criteria (PICOS1 framework).

Population Adults with or at risk for (as deemed by study authors) HIV and/or opioid use disorder; n ≥ 10
Intervention Screening or treatment for both HIV and opioid use disorder occurring within the same treatment setting or across settings that are integrated at the organizational level
Comparison Screening or treatment for HIV and opioid use disorder occurring not in integrated settings, which may include a historical control, or a comparison between two integrated care strategies
Outcome HIV or opioid use disorder screening uptake, HIV or opioid use disorder quality of care measures, HIV or opioid use disorder biochemical outcomes, or general health outcomes
Study design Randomized trials, prospective cohort studies with controls, historically controlled trials
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PICOS = Population, Intervention, Comparison, Outcome, Study Design