Skip to main content
. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 Dec 18;127:154–164. doi: 10.1016/j.yjmcc.2018.12.007

Fig. 1. Markers of division and cell-cycle status.

Fig. 1.

FUCCI fluorescence mKO (red) presents in G1 phase, and AzG (green) presents during S/G2/M phases, where during the G1/S transition both fluorescence (mKO/AzG) present simultaneously and merge into a yellow color. BrdU or Edu, both thymidine analogs incorporate into DNA during synthesis (cyan). Phosphorylated Histone 3 (pHH3) is responsible for chromatin condensation and is thus present during G2 through M phase (magenta). Nuclear antigen Ki67 is present from G1 to M phase (emerald). PCNA is presents between G1 and G2 phase in response to DNA synthesis (burgundy). Anillin plays a role in creating the cleavage furrow formation and begin to accumulate in late G2 through late M phase (blue). Aurora B plays a role in mitosis, present from G2 through M phase (sand).