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. 2019 Jun 21;9:9022. doi: 10.1038/s41598-019-45440-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

rPfMSP2 and rPfMSP2/8 vaccines induce antibody that recognizes native P. falciparum antigen. (A) Pools of anti-PfMSP2 and anti-PfMSP2/8 rabbit sera were used to determine recognition of native P. falciparum antigen via immunoblot of parasite lysate. (B) Detection of parasite-associated antigen using pooled sera was determined via indirect immunofluorescence assay of fixed, late-stage schizonts. Adjuvant control sera were also tested in both assays, serving as negative controls (R, reduced; NR, non-reduced).