Table 1.
Overview of bacteriocins and human AMPs used in this study
Peptide | Sequence | Source | Mode of action |
---|---|---|---|
Lugdunin | CvWlVvV (cyclic thiazolidine) | Staphylococcus lugdunensis | Unknown |
Gallidermin | IASKFLCTPGCAKTGSFNSYCC | Staphylococcus gallinarum | Inhibition of cell wall biosynthesis |
Pro-gallidermin | MEAVKEKNELFDLDVKVNAKESNDSGAEPRIASKFLCTPGCAKTGSFNSYCC | Staphylococcus gallinarum | Inactive pro-form |
Nisin | ITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK | Lactococcus lactis | Pore formation, inhibition of cell wall biosynthesis |
DCD-1 | SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSV | Eccrine sweat glands | Pore formation |
DCD-1L | SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL | Eccrine sweat glands | Pore formation |
LL-37 | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES | Epithelial cells, leukocytes | Pore formation |
AMPs, antimicrobial peptides