Figure 3.

(A) Thermographs of mice injected with the RBC-AuNPs and the pristine PVP-AuNPs after 48 hours. The mice were irradiated with an 850 nm laser (1 W/cm²). (B) Tumor site temperature based on thermographs of mice in (A). Red line indicates the lowest cancerous cells ablation temperature –42°C. (C) Graphs of the average tumor volume. (D) Graphs of the average mouse body weight. (E) Graphs of the mouse survival ratio. (F) Thermographs of tumor-bearing mice under an 808 nm NIR laser exposure (5 W/cm²) for 0–300 seconds. (G) After intravenous injection with MNCs and MNC@RBCs, T2-weighted MR images of tumor-bearing mice were taken at different time points. Blue arrows indicate the tumor locations. ^41,53 Reprinted from Biomaterials, 92, Ren X, Zheng R, Fang X, et al. Red blood cell membrane camouflaged magnetic nanoclusters for imaging-guided photothermal therapy. 13–24, Copyright (2016), with permission from Elsevier.⁴¹ Reprinted with permission from Piao J-G, Wang L, Gao F, You Y-Z, Xiong Y, Yang L. Erythrocyte membrane is an alternative coating to polyethylene glycol for prolonging the circulation lifetime of gold nanocages for photothermal therapy. ACS Nano. 2014;8(10):10414–10425. doi:10.1021/nn503779d. Copyright 2014 American Chemical Society.⁵³

Notes: Fig 3 parts F, G is taken from reference 41, parts A-E is taken from reference 53.

Abbreviations: MNCs, iron oxide magnetic nanoclusters; MNC@RBCs, RBC membrane camouflaged iron oxide magnetic clusters; MF, magnetic field.