(A) TEM images of ICNPs. (B) Fluorescence images of MCF-7 cells stained with calcein-AM/PI, which were treated with laser, ICG + laser, INPs + laser, or ICNPs + laser. Scale bar, 100 µm. (C) Confocal microscopy images of MCF-7 cells treated with free ICG, INPs, or ICNPs. (D) The infrared thermographic images of ICNPs, INPs, free ICG and PBS after 8 mins continuous laser irradiation at power density 1 W/cm2. (E) Immunogold TEM images of B16-F10, RBC, RBC-B16 membrane, and CuS@[RBC-B16] NPs samples probed for CD47 (red arrows, large gold) and gp100 (yellow arrows, small gold), followed by negative staining with uranyl acetate (scale bars =100 nm). (F) The cell viabilities of B16-F10 cells with different combination of CuS@[RBC-B16] NPs, DOX, NIR. (G) Confocal fluorescent microscopy images of live/dead staining of B16-F10 cells treated with different materials with or without 1,064 nm NIR laser irradiation at power dense 1.0 W/cm2. Scale bar is 100 µm. Reprinted with permission from Chen Z, Zhao P, Luo Z, et al.Cancer cell membrane-biomimetic nanoparticles for homologous-targeting dual-modal imaging and photothermal therapy. ACS Nano. 2016;10(11):10049. doi:10.1021/acsnano.6b04695. Copyright 2016 American Chemical Society.28 Reprinted with permission from Wang D, Dong H, Li M, et al. Erythrocyte-cancer hybrid membrane camouflaged hollow copper sulfide nanoparticles for prolonged circulation life and homotypic-targeting photothermal/chemotherapy of melanoma. ACS Nano. 2018.12(6);5241–5252. Copyright 2018 American Chemical Society.75
Notes: Fig 7 parts A-D, is taken from reference 28, 7 parts E-G is taken from reference 75.
Abbreviations: INPs, PEGylated phospholipid and soybean lecithin shell coated ICG-PLGA core.