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. 2019 May 11;116(12):2314–2330. doi: 10.1016/j.bpj.2019.05.008

Figure 4.

Figure 4

Microsecond to millisecond timescale motions in the WT and QM Tiam2 PDZ domain. Representative relaxation dispersion curves from the Tiam2 WT (A) and QM (C) PDZ domains collected at 500 (open circle) and 800 (closed circle) MHz are shown. Curves for each residue with Rex are shown in Figs. S3 and S4, whereas their fitted parameters are indicated in Tables 1 and 2. Error bars were determined by the analysis of peak intensities from duplicate experiments. (B and D) Structural models of WT and QM Tiam2 PDZ with highlighted residues showing relaxation dispersion are shown. To see this figure in color, go online.