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. 2019 May 21;116(12):2304–2313. doi: 10.1016/j.bpj.2019.05.013

Figure 1.

Figure 1

The primary sequence of IAPP and AGE-IAPP. The first amino acid of AGE-IAPP was mutated by CML and AGE-IAPP was used to study the effect of protein glycation on IAPP aggregation. Two peptides were chemically synthesized with amidated C-terminus and contain a disulfide bond between Cys2 and Cys7. To see this figure in color, go online.