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. 2019 May 21;116(12):2304–2313. doi: 10.1016/j.bpj.2019.05.013

Figure 8.

Figure 8

Cell viability of MIN6 cells following incubation with various concentration of IAPP, AGE-IAPP, and protein mixtures including IAPP and AGE-IAPP at a 1:1 ratio. MIN6 pancreatic β cells were treated with various concentrations of IAPP, AGE-IAPP, and IAPP:AGE-IAPP = 1:1 for 4 or 24 h before cell viability was measured. Cell viability was determined by Alamar Blue assay and compared to that of cells treated with vehicle (100% cell viability). The statistical significance between IAPP and AGE-IAPP was indicated by one-way ANOVA (∗∗∗∗p < 0.0001; ∗∗∗p < 0.001; ∗∗p < 0.005).