Table 1. Susceptibility of P. aeruginosa to antipseudomonal agents tested.
| Variables | N (%) of isolates | ATM | C/T | FEP | CAZ | IPM | MEM | TZP | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MIC50/90 | %S | MIC50/90 | %S | MIC50/90 | %S | MIC50/90 | %S | MIC50/90 | %S | MIC50/90 | %S | MIC50/90 | %S | ||||||||
| Total isolates collected from patients | 1,209 (100) | 8/32 | 66 | 0.5/2 | 95 | 4/32 | 76 | 4/64 | 78 | 2/16 | 68 | 0.5/16 | 74 | 8/128 | 73 | ||||||
| Isolates based on location | |||||||||||||||||||||
| ICU* | 541 (44.7) | 8/64 | 66 | 1/2 | 95 | 4/32 | 75 | 4/64 | 77 | 2/16 | 67 | 1/16 | 72 | 8/256 | 70 | ||||||
| Respiratory | 436 (36.1) | 8/64 | 63 | 1/4 | 94 | 4/32 | 71 | 4/64 | 75 | 2/32 | 63 | 1/16 | 69 | 8/256 | 68 | ||||||
| Blood | 104 (8.6) | 8/32 | 75 | 0.5/1 | 99 | 4/8 | 90 | 2/16 | 88 | 2/16 | 83 | 0.5/8 | 88 | 8/64 | 80 | ||||||
| Non-ICU | 668 (55.3) | 8/32 | 66 | 0.5/2 | 96 | 4/32 | 78 | 2/32 | 79 | 2/16 | 68 | 0.5/16 | 75 | 8/128 | 76 | ||||||
| Respiratory | 474 (39.2) | 8/64 | 64 | 1/4 | 95 | 4/32 | 73 | 4/64 | 74 | 2/16 | 67 | 0.5/16 | 73 | 8/256 | 72 | ||||||
| Blood | 194 (16.0) | 8/32 | 72 | 0.5/2 | 98 | 2/16 | 89 | 2/8 | 90 | 1/16 | 71 | 0.5/8 | 81 | 8/32 | 87 | ||||||
| Isolates based on source | |||||||||||||||||||||
| Blood | 298 (24.6) | 8/32 | 73 | 0.5/2 | 98 | 2/16 | 89 | 2/16 | 89 | 2/16 | 75 | 0.5/8 | 83 | 8/32 | 84 | ||||||
| ICU | 104 (8.6) | 8/32 | 75 | 0.5/1 | 99 | 4/8 | 90 | 2/16 | 88 | 2/16 | 83 | 0.5/8 | 88 | 8/64 | 80 | ||||||
| Non-ICU | 194 (16.0) | 8/32 | 72 | 0.5/2 | 98 | 2/16 | 89 | 2/8 | 90 | 1/16 | 71 | 0.5/8 | 81 | 8/32 | 87 | ||||||
| Respiratory | 910 (75.3) | 8/64 | 64 | 1/4 | 95 | 4/32 | 72 | 4/64 | 74 | 2/16 | 65 | 1/16 | 71 | 8/256 | 70 | ||||||
| ICU | 436 (36.1) | 8/64 | 63 | 1/4 | 94 | 4/32 | 71 | 4/64 | 75 | 2/32 | 63 | 1/16 | 69 | 8/256 | 68 | ||||||
| Non-ICU | 474 (39.2) | 8/64 | 64 | 1/4 | 95 | 4/32 | 73 | 4/64 | 74 | 2/16 | 67 | 0.5/16 | 73 | 8/256 | 72 | ||||||
*, total number of isolates 1,208 (one patient in ICU was missing source of sample). ATM, aztreonam; C/T, ceftolozane/tazobactam; FEP, cefepime; CAZ, ceftazidime; IPM, imipenem; MEM, meropenem; TZP, piperacillin/tazobactam; MIC, minimum inhibitory concentration; %S, percent susceptibility; ICU, intensive care unit.