Skip to main content
. 2019 May;11(5):1896–1902. doi: 10.21037/jtd.2019.05.13

Table 2. Potency of antipseudomonal agents in the presence of various phenotypic resistance profiles.

Phenotype profile % susceptibility
N [%] ATM C/T FEP CAZ IPM MEM TZP
NS to ATM 410 [34] 88 44 49 46 45 35
NS to C/T 55 [5] 11 9 7 25 22 15
NS to CAZ 267 [22] 21 81 20 39 41 14
NS to FEP 287 [24] 20 83 25 38 35 19
NS to IPM 392 [32] 44 90 54 59 27 49
NS to MEM 316 [26] 28 86 41 50 10 36
NS to TZP 322 [27] 17 85 28 29 39 38 -
NS to carbapenemsa 432 [36] 41 89 54 60 7 25 48
MDR 153 [13] 12 74 6 10 5 6 8
NS to 1 or more agentb 648 [54] 37 92 56 59 40 51 50
NS to all agentsc 118 [10] 75

Aztreonam (ATM), ceftolozane/tazobactam (C/T), cefepime (FEP), ceftazidime (CAZ), imipenem (IPM), meropenem (MEM) and piperacillin/tazobactam (TZP) against P. aeruginosa. a, carbapenem non-susceptibility defined as non-susceptible to IPM or MEM with MIC of >2 mg/L; b, antipseudomonal agents tested in this study (ATM, C/T, FEP, CAZ, IPM, MEM, and TZP); c, antipseudomonal agents tested in this study other than the compound of interest (ATM, FEP, CAZ, IPM, MEM, and TZP). MDR, multidrug resistant; MIC, minimum inhibitory concentration; NS, non-susceptible.